Title: High resolution fMRI: An introductory course for data acquisition and analysis challenges.
Support: This lecture series is finanzially supported by the FPN-MBIC-school. The session on sequences and sequence artifacts is supported (in kind) by the York-Maastricht-partnership grant. Faruk Omer Gulban works for Brain Innovation.
Coordinators: Laurentius (Renzo) Huber & Omer Faruk Gulban, Cognitive Neuroscience Department
Email: renzohuber@gmail.com or faruk.gulban@maastrichtuniversity.nl
Dates: 7, 14, 21, 28 July 2020 (4 sessions in total), 3pm to 4:30pm.
Video Conference Zoom link (note that these sessions may be recorded): https://maastrichtuniversity.zoom.us/meeting/register/tJAvcu-qpj8sHNVD71Vcu95et-R14QKRs22T
Objective(s):
This course will be an introduction to acquiring and analyzing high resolution (<1mm) functional magnetic resonance imaging (fMRI) data. The course participants will acquire data and analyze with the guidance of the course coordinators.
After this course, participants will be able to:
- Give a rough overview of the seminal papers, challenges and prospects of laminar fMRI
- Discuss the most common artifacts at the scanner and how to address them
- Make more informed decisions for their own high resolution fMRI acquisitions.
- Use image registration and segmentation methods to address some of the most challenging analysis steps.
Literature: There will be no textbook. Individual articles will be suggested for the sessions 3 and 4.
Form of assessment: Attendance (all 4 sessions).
Detailed schedule
-
Tuesday July 7th, 3pm-5:30pm, Introduction
- [3:00-3:30pm] Getting to know each other
- [4:30-4:00pm] Introduction lecture from Faruk
- [4:00-4:30pm] Introduction lecture from Renzo about the layer-(f)MRI field
- Divisions of projects (see table below), topics can be:
- A paper chosen from this list of papers.
- A software presentation.
- A presentation from their PhD project.
- List of topics below.
-
Tuesday July 14th, High-res EPI scanning tutorials and artifacts (virtual)
- [3:00-4:00pm, Renzo] Virtual 7T MRI scan session.
- Step-by-step optimizing sub-millimeter fMRI.
- Optimizing GRAPPA parameters.
- Detecting and correcting high-res EPI artifacts.
- TR, coverage and resolution trade-offs.
- Phase encoding direction GRAPPA artifacts.
- Anatomical sequences for 0.5 mm resolution.
- [4:00-4:30pm, Faruk] Segmentation of 7T MR images.
- [Preparation reading] Helms, G. (2016). Segmentation of human brain using structural MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 29(2), 111–124. [or download from here]
- [4:30pm] Discussing preparation for next week: installing LAYNII, and downloading data.
- [3:00-4:00pm, Renzo] Virtual 7T MRI scan session.
-
Tuesday July 21st, LAYNII Tutorial
- [3:00-3:30pm, Faruk] Continuation of segmentation.
- [3:30-4:30pm, Renzo] Click/code-along LAYNII tutorial for generating layers.
- Preparation:
- Install LAYNII from github, e.g. with these https://layerfmri.com/laynii-setup/.
- Download example data from Open neuro: https://openneuro.org/datasets/ds002274/versions/1.0.2. Alternative download link: here.
- It is vital to have a nifty viewer installed. E.g. ITK-snap or FSLeyes or FSLfiew.
- It would be very helpful to have AFNI installed too.
- Useful commands:
- Useful links:
- How many layers to reconstruct: blog post here
- Which layering algorithm to use: blog post here and here
- Preparation:
-
Tuesday July 28th, 3:00pm-5:30pm, Attendees give 8min presentations
- Logan: Methods to correct for venous biases in GE-BOLD.
- Yawen: Brightness induction.
- Miriam: Odd-ball detection.
- Kirsten: High-level feedback to V1.
- Johannes: Paper discussion of Peter Koks Kanizsa triangle study.
- Dominika: Paper discussion of Andrew Persichetti’s imaginary finger movement study.
- Minye: EPI distortion correction and individual differences.
- Ceren: Deep brain structures for auditory perception. (canceled)
- Marco: Multi-sensory motion perception. (canceled)
Survey from FPN/CN: https://maastrichtuniversity.eu.qualtrics.com/jfe/form/SV_51tkipZ2PRkknZj?Q_CHL=qr
Slides:
- Introduction session Renzo’s slides: https://drive.google.com/file/d/1bGE7V4PZNldsOH8Xs49moMulxNeOUhNw/view?usp=sharing
Introduction of the course
Introduction to layer-fMRI
- Introduction session Faruk’s slides: https://docs.google.com/presentation/d/1tB9-T6KIoUUPWPM2ptjo-qUlQ_Z3K-n5expM3a-1XwQ/edit?usp=sharing
- Hands on scanning slides: https://drive.google.com/file/d/119ixLnRokCPRQ_-W-I_immEXClfsSgyJ/view?usp=sharing
- Introduction to Segmentations.
- Hands on Layering: https://layerfmri.com/laynii-setup/
- Hands on segmentation:
- Participants contributions:
- Logan: Methods to correct for venous biases in GE-BOLD
-
- Yawen: Brightness induction.
-
- Miriam: Odd-ball detection.
-
- Johannes: Paper discussion of Peter Koks Kanizsa triangle study.
-
- Dominika: Paper discussion of Andrew Persichetti’s imaginary finger movement study.
-
- Minye: EPI distortion correction and individual differences.